I did the IsaGenix one. I think it cost about $300 total if I'm not mistaken. I lost a bunch of weight and did feel a lot better after. The MLM aspect of it bothered me and it got expensive to maintain after the first month. Honestly, I think if you are eating healthy and drinking a LOT of water, the cleanse routines are unnecessary.
The key to the IsaGenix program/cleanse is the meal replacement shakes. Have 1-2 every day with other sensible eating and you'll lose weight. But there are better shakes out there (the one Armen posted IMO) or you could just make your own with frozen fruit & protein powder etc.
If you want to try the IsaGenix shakes, I have an unopened one that you could have. would last about 2-3 weeks.